Nootropics Raw Coluracetam CAS: Smart Drugs for Brain Improvement
Description:
Coluracetam Review 135463-81-9
Product Name: Coluracetam MKC-231
Chemical Name: N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-
1-yl)acetamide
CAS No.: 135463-81-9
Formula: C19H23N3O3
Purity:99%
Molecular Weight:341.40
Appearance:white crystal powder
Boiling Point:634.1C at 760 mmHg C
Description: Coluracetam (BCI-540) is a nootropic drug of the racetam family. (for research only
Application:mainly applied to promote intellectual product. /raw material used in Synthesis/
pharmaceutical raw material
Coluracetam (INN) (code name BCI-540; formerly MKC-231) is a nootropic agent of the racetam family.[1] It was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depressive disorder (MDD), which was preceded by being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.[2] Findings from phase IIa clinical trials have suggested that it would be a potential medication for comorbid MDD with generalized anxiety disorder (GAD).[3] BrainCells Inc is currently[when?] out-licensing the drug for this purpose.[4][full citation needed] It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.[medical citation needed]
Coluracetam has been shown to reverse the loss of choline acetyltransferase production in the medial septal nucleus of rats exposed to phencyclidine (PCP), and is considered a potential therapeutic drug for schizophrenia.
