Filitra 40 mg, which contains Vardenafil, is used to treat erectile dysfunction (ED). It can interact with various medications, potentially causing adverse effects or reducing the effectiveness of either the Filitra or the other medications. Here’s a guide to when Filitra 40 mg might interact with other drugs: Major Drug Interactions Nitrates: Examples: Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate. Interaction: Can cause a severe drop in blood pressure, leading to dizziness, fainting, or even heart attack or stroke. Other PDE5 Inhibitors: Examples: Sildenafil (Viagra), tadalafil (Cialis), avanafil (Stendra). Interaction: Combining with other PDE5 inhibitors can increase the risk of side effects such as headaches, dizziness, or an extended erection (priapism). Alpha-Blockers: Examples: Doxazosin, terazosin, prazosin. https://www.flatmeds.com/product/filitra-40-mg/ : Can cause a significant drop in blood pressure, leading to symptoms such as dizziness or fainting. Antifungals and Antibiotics: Examples: Ketoconazole, itraconazole, erythromycin. Interaction: These can increase the levels of Vardenafil in the blood, potentially leading to increased side effects. HIV Protease Inhibitors: Examples: Ritonavir, saquinavir, nelfinavir. Interaction: Can also increase the levels of Vardenafil in the blood, leading to a higher risk of side effects. Certain Antidepressants: Examples: SSRIs (Selective Serotonin Reuptake Inhibitors) like fluoxetine, paroxetine. Interaction: May affect the metabolism of Vardenafil, though this interaction is usually less significant. Moderate Drug Interactions Blood Pressure Medications: Examples: Beta-blockers, calcium channel blockers. Interaction: May enhance the blood pressure-lowering effects of Vardenafil. Antacids: Examples: Aluminum hydroxide, magnesium hydroxide. Interaction: Can reduce the absorption of Vardenafil if taken simultaneously. General Precautions Consult Your Doctor: Always inform your healthcare provider of all the medications, including over-the-counter drugs and supplements, that you are taking. Avoid Self-Medication: Do not start or stop any medications without professional advice. If you have concerns about potential interactions or need personalized advice, consult with a healthcare professional to ensure safe and effective use of Filitra 40 mg.