When the Buccaneers (10-3) host the Saints (6-7) on "Sunday Night Football" in Week 15 of the 2021 NFL season (8:20 p.m. ET, NBC), they Joe Schobert Jersey will be looking to wrap up the NFC South title. Tampa Bay was a wild-card playoff team behind New Orleans when it made the run to win Super Bowl 55 last season.A win would mark another division crown for Tom Brady with a second team. The Saints are looking at their four-year reign over the South coming to a close.The Buccaneers can make a statement trying to re-establish their status as clear Super Bowl favorites. The Saints are looking to sweep the Bucs for a second consecutive regular season.Here's everything to know about betting on Saints vs. Buccaneers in Week 15, including updated odds, trends andexpert's prediction for "Sunday Night Football."NFL WEEK 15 PICKS: | Spread: Antonio Callaway Jersey Buccaneers by 11.5Over/under: 45.5Moneyine:Saints +420, Buccaneers -560The Buccaneers have been double-digit favorites since the initial lines, another lopsided spread in a division game for SNF. The Bucs are rolling like they were last December while the Saints keep fading with limited offense and shaky pa s defense.(betting odds per ) The Saints lead the series 38-22. They won 36-27 on Halloween in New Orleans. Last season, they won 34-23 to open the year at home and also won 38-3 in Tampa. But the Buccaneers won the key playoff meeting in between, 30-20. That's Tampa Bay's only win in the past seven meetings. 72 percent of spread bettors are siding with the Saints to cover the ma sive number despite being on the road, where the Buccaneers have dominated at home.60 percent of over/under bettors think the total is too low given the offensive potency of both teams at times. The Bucs can handle much of the scoring on their own to push the total Ricardo Louis Jersey around 50.The Saintsare 4-6 against the spread and 4-6 straight up in their past 10 games. The total has gone over six times. The Bucs are 6-4 ATS and 8-2 SU in their past 10 games. The total has gone under six times. The Saints' offensive injuriesThe Saints are once again mi sing starting tackles Terron Armstead and Ryan Ramczyk because of knee injuries. Wide receiver Michael Thomas has mi sed the entire year with his ankle injury, leaving the Saints' with arguably the league's worst wide receiver corps. There will be plenty of Taysom Hill as a runner with support from the versatile Alvin Kamara as New Orleans tries to move the ball on the same level as Brady.The Buccaneers' defensive injuriesThe Bucs will be hurting again in the secondary with the safeties and subpackages being the concern as Jordan Whitehead (calf) and Antoine Winfield Jr. (foot) are listed as questionable andJamel Dean and Richard Sherman are set to mi s the game. The Bucs have been managing on the back end all season and their top linebacker corpswill be more critical to winning this game.The running gamesTampa Bay Is No. 3 against the run. New Orleans is No. 6 against the run.Tampa Bay has the No. 25 rushing offense, but it is effective running Morgan Burnett Jersey the ball when needed with Leonard Fournette (ankle-questionable). New Orleans is more dependent on the ground, with the No. 14 rushing offense. The Bucs won't mind pa sing 50 times to win the game with Brady; the Saints want Hill probably to throw fewer than 20 times. 48.2 percent. Seth DeValve Jersey That's the Buccaneers' conversion rate on third downs this season. The Saints' defense has allowed a low conversion rate of 37.9 percent. The Bucs get it done with great early-down pa sing with Brady or chunk runs, setting up third-and-manageable situations consistently. Their big offensive strength, No. 2 in the league, can flex here to thwart the Saints. Hill and Kamara will try to run the Saints into competitivene s but their continued limitations in the pa sing game hurt here given the Bucs' secondary is still dealing with a lot of injuries. The Bucs' pa s rush working against backup tackles will be effective and Brady will make sure the game script isn't favorable by jumping on the many weakne ses of the Saints' own pa s defense.Buccaneers 31, Saints 20