Exosomes are small vesicular structures that represent a novel source of biomarkers for the state of the cells from which they are derived. Typically, quantification is very important to understand basic biological relationships between exosomes and their parent cells, as well as the underlying interpretation of exosome signals. As interest in exosomes expended, the number of methods for quantifying exosomes has increased. In previous studies, three groups have illustrated the importance of quantifying exosomes, examining the stoichiometry of miRNAs per exosome. For example, Akers et al. isolated extracellular vesicles, primarily exosomes, from cerebrospinal fluid (CSF) samples and then measured the number of exosomes via nanosight nanoparticle tracking analysis and the total content of specific miRNAs by qRT-PCR. Creative Biolabs offers a variety of techniques for exosome quantification to satisfy our customer’s needs.