Sildigra 100 mg is a medication used for the treatment of erectile dysfunction (ED). It contains sildenafil citrate, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. While generally safe and effective for most individuals with ED, there are certain medical conditions that may require adjustments in dosage or complete avoidance of Sildigra 100 mg due to potential complications or interactions. These conditions include:
Cardiovascular diseases: Sildenafil can interact with medications used to treat cardiovascular conditions, such as nitrates (e.g., nitroglycerin) and alpha-blockers, leading to a significant drop in blood pressure. Therefore, individuals with heart disease, angina, hypertension, or recent history of heart attack or stroke should use Sildigra cautiously under medical supervision.
Liver or kidney disorders:
Sildigra 100 mg is metabolized in the liver and excreted primarily through the kidneys. Patients with severe liver or kidney impairment may require dosage adjustments or avoidance of Sildigra due to the potential for increased drug levels in the body, which can lead to adverse effects.
Priapism: Sildigra should be used with caution in individuals predisposed to priapism, a prolonged and painful erection lasting more than four hours, as it can lead to permanent damage to the penis. This includes individuals with conditions such as sickle cell anemia, multiple myeloma, or leukemia.
Retinal disorders: Sildenafil has been associated with rare cases of visual disturbances, including blurred vision, changes in color vision, and in some cases, non-arteritic anterior ischemic optic neuropathy (NAION). Individuals with retinal disorders such as retinitis pigmentosa should use Sildigra cautiously and seek medical advice if experiencing any vision changes.
Hypersensitivity: Individuals with a known hypersensitivity or allergy to sildenafil or any of the inactive ingredients in Sildigra should avoid using the medication.
Bleeding disorders: Sildenafil can potentiate the antiplatelet effects of drugs like aspirin or anticoagulants, increasing the risk of bleeding. Patients with bleeding disorders or those taking anticoagulant therapy should use Sildigra cautiously and under medical supervision.
Severe deformity of the penis: Sildenafil may exacerbate anatomical deformities of the penis, such as Peyronie's disease, and should be used with caution in such cases.
It's crucial for individuals considering Sildigra or any medication for ED to consult with a healthcare professional, who can assess their medical history and determine the appropriateness of the medication and dosage adjustments based on individual health factors.