High Purity API Idra-21 Powder for Nootropic Supplyment 22503-72-6 Idra21



IDRA-21 is a relatively new nootropic compound. It works as an ampakine stimulant drug and is currently being researched in regards to its effects in memory improvement, cognitive enhancement, stimulation, and reversing cognitive deficits.

Powerful Drug
IDRA-21 is an ampakine drug derived from benzothiadiazine and a positive allosteric modulator of glutamate AMPA receptors. IDRA-21 shows nootropic effects in animal studies, significantly improving learning and memory. It is around 10-30 times more potent than aniracetam in reversing cognitive deficits induced by alprazolam or scopolamine, and produces sustained effects lasting for up to 48 hours after a single dose. The mechanism for this action is thought to be through promoting the induction of long-term potentiation between synapses in the brain.

In comparison to the benzoylpiperidine derived ampakine drugs, IDRA-21 was more potent than CX-516, but less potent than CX-546. Newer benzothiadiazide derivatives with greatly increased potency compared to IDRA-21 have been developed, but these have not been researched to the same extent, with the benzoylpiperidine and benzoylpyrrolidine CX-series of drugs being favoured for clinical development, most likely due to more favourable toxicity profiles at high doses.
IDRA-21 Benefits
1. Increase in cognition.
2. Increase Task Accuracy
3. Increases in Short Term Memory
4. Potential Therapeutic Effects On Schizophrenia
5. Potental Therapeutic Effects On Depression
6. Neuroprotection